Wine and beer can provide some phenolic nutrients, however they can also be a migraine trigger for some migraine sufferers (like me). Some of the mood lifting benefits of wine are provided by the free (not-bound-within-a-larger-protein) amino acid content found in wine while other free amino acids in wine may be part of the migraine cause.
Due to a genetic difference I discovered that I have, I found a bulk supplier of powdered free amino acids and tried Methionine and Glycine in water. A half teaspoon of each provides a cheerful mood boost without causing excess energy boosting effects – I tried a teaspoon of each initially and it could cause sleeplessness if taken late in the evening and almost too much of a energy boost to the point of having an increased heart rate. Several free amino acids act within the brain to activate or inhibit neurons/brain cells.
The free amino acids are acidic and cause a puckery tart wine or lemonade effect when added to water. Adding an ounce or two of juice, 2-4 Tablespoons of a 100% Purple Grape Juice or Cherry Juice or Black Currant Juice, can add a hint of sweetness and anthocyanins and makes the resulting beverage slightly more juice or wine like.
A deficiency of Methionine whether due to a genetic difficulty in metabolism such as I have or due to a dietary lack can increase the body’s need for Nrf2. (G10.7) A deficiency of Nrf2 could negatively affect the body’s supply of the amino acids Glycine and Serine as it is involved in their biosynthesis pathways. (G10.13) The pathway, called the pentose phosphate pathway, is shown in Figure 2: (G10.14). So speculatively Glycine wouldn’t be helping make Nrf2 but if there was a problem with supply of Nrf2 then there might be a shortage of Glycine or Serine, and they do have biological roles throughout the body. Glycine also has roles in the brain to inhibit overactivation and therefore may help if anxiety or other mental illness symptoms are present.
Yes, but what about the Wine and Beer? - Two servings of alcoholic beverages for a man or one for a smaller woman or man has been found to provide some cardiovascular health benefits - enjoy responsibly and designate a driver if time isn’t available to detoxify the alcohol, approximately one hour per serving is needed to recover from the physical effects of alcohol on thinking and reaction time. Whiskey and other liquors may also contain some beneficial nutrients depending on the ingredients and processing and age of the liquor. (G10.26) The serving size of alcoholic beverages varies based on the concentration of alcohol. Serving sizes and more information about the medical research regarding alcohol is available on the Harvard T. H. Chan School of Public Health website: Alcohol: Balancing Risks and Benefits. (P.alcohol)
Fermenting fruit and other starchy plants or grains was a way to preserve the nutrients when there was no freezer or refrigerator. Jagermeister is a flavorful alcoholic beverage that was sold as a cough medicine and digestive aid. It may have health benefits because of the many nutritious seasonings used in the recipe (G10.27) but moderation is still important with alcoholic beverages. Some people have trouble stopping once they start drinking and none might be the best serving size for them.
See the section I: Addiction or Starvation? For more information about a possible genetic difference that may be involved in addictive alcohol or other substance use.